Obesity and long-term prognosis in heart failure: the paradox persists.

نویسندگان

  • Elisabet Zamora
  • Josep Lupón
  • Agustín Urrutia
  • Antoni Bayes-Genis
چکیده

of the surgical technique due to the absence of pericardial closure after initial heart surgery and the development of adhesions. Reoperation status remained an independent predictor of operative death after adjusting for confounding factors. The aorta, right ventricle, and bypass grafts may adhere to the underside of the sternum and can be easily injured at reoperation. In-hospital mortality for patients undergoing cardiac reoperation is higher than that of patients undergoing primary surgical intervention4,5. Previous surgical revascularization is a predictive factor for early mortality.6 One of the methods thought to reduce the morbidity and mortality associated with reoperation is the use of pericardial substitutes, serving to conserve the anatomical relationship. The heterogeneity of available materials, both synthetic and biological, is an indicator of the fact that an ideal tissue substitute has yet to be identified. In conclusion the findings from the patient presented here with the results from a shortterm study suggest that the biodegradable collagen-elastin membrane constitutes a safe, effective option for pericardial closure. At reoperation, the use of this membrane appears to reduce the risk of structural damage during dissection while also reducing surgery time and morbidity/mortality.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Controversies in Obesity Treatment

The markedly high prevalence of obesity contributes to the increased incidence of chronic diseases, such as diabetes, hypertension, sleep apnea, and heart disease. Because of high prevalence of obesity in almost all countries, it has been the focus of many researches throughout the world during the recent decades. Along with increasing researches, new concepts and controversies have been emerge...

متن کامل

Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure.

Obesity has reached epidemic proportions in the United States and worldwide. Considering the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function, and other risk factors for heart failure (HF), including hypertension and coronary heart disease, HF incidence and prevalence, not surprisingly, is markedly increased in obese patients. Nevertheless, as with ...

متن کامل

“Obesity Paradox” in Heart Failure: The Possible Role of Progenitor Endothelial Cell Dysfunction

The “obesity paradox” phenomenon is referred to as a U-shaped curve between long-term prognosis and body mass index in heart failure patients. There is a large body of evidence regarding the regulatory role of visceral adipose tissue-related adipocytokines in activity of endogenous repair system. The reparation of myocardium and endothelium may strongly enhance by differentiation and mobbing of...

متن کامل

Obesity, Heart Failure, and Obesity Paradox

The incidence and prevalence of obesity are fast increasing worldwide. Various indices have been used to measure and assess obesity. The body mass index (BMI) is the most common and practical of these indices. Overweight and obesity exert considerable adverse effects on the cardiovascular system. These effects are mediated through various neurohormonal and cytokine pathways, most of which are i...

متن کامل

The "Obesity Paradox" Is Not a Paradox: Time to Focus on Effective Treatments.

I recently read the editorial comment by Lavie and Ventura (1) with interest but also with disappointment. My disappointment is because several papers from different authors have illustrated that the reported relationship between obesity and survival from heart failure occurs because all of the observational analyses suffer from a very serious bias if one is exploring causal effects—for 2 examp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Revista espanola de cardiologia

دوره 63 10  شماره 

صفحات  -

تاریخ انتشار 2010